出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：The use of nanoparticles has been applied in several areas of pharmacology, due to its advantages before absorption, distribution and its effect on disease, especially when it is compose of natural products due to its ability to reduce possible toxic effects of the final product. The study aimed to analyze the effect of Helianthus Annuus extract (AgNP@Ha) in the synthesis of a silver nanoparticle and to evaluate its antimicrobial action against gram-positive, gram-negative bacteria and fungi. The production of the nanoparticle was carried out by stirring over a heated magnetic plate until the complete configuration of the nanoparticle was formed, then, the extract was used to stabilize the nanoparticle, its size was verified by means of UV-VIS. Microbiological analysis was performed on a plate, measuring the size of the inhibitory halo formed. An AgNP@Ha 414 nm that were stabilized using sunflower was obtained with halo formation effect on S. aureus (16 mm), E. coli (12 mm) and P. aeruginosa (10 mm) strains, while AgNPs that were not stabilized with sunflower did not show the inhibitory halo. Through this research it was possible to prove the improvement of pharmacological effect and production efficiency of silver nanoparticles when using sunflower seed extract as a stabilizer The synthesis of silver nanoparticles using the extract of Helianhtus annuus seeds promoted a more environmentally friendly, simple, efficient and low cost approach to obtain nanoparticles, becoming an excellent product with antimicrobial potential to be marketed in addition to serving as a subsidy for further research.
