出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：New ready-to-use calcium silicate sealers (i.e., Bio-C Sealer and Sealer Plus BC) have proven to be bioactive and biocompatible materials. However, its antimicrobial activity has not yet been fully unraveled. The aim of this study was to evaluate the antimicrobial activity of bioceramic sealers (Bio-C Sealer, Sealer Plus BC and BioRoot RCS) in comparison with resin-based sealers (AH Plus, Sealer Plus and MTA Fillapex). Fresh sealers were tested against Enterococcus faecalis biofilms using direct and indirect contact tests. Colony forming units were counted after 24 hours. Additionally, crystal violet assay was used to evaluate the effects of sealer extracts on biofilm biomass. Optical density measurements were used to quantify biomass. Bioceramic sealers showed greater antimicrobial activity than resin-based sealers when in direct contact with biofilms (P E. faecalis biofilms in direct and indirect tests. Furthermore, Sealer Plus BC showed the best effect on biofilm biomass.
