出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：The pharmacological potential from natural bioactives has increasingly driven the pharmaceutical market, which seeks to enhance therapies and implement new molecules and bioactive products. In this context, the fruits of Hylocereus polyrhizus have shown a great nutritional value and an indication of the presence of possible secondary metabolites in its composition. In this context, this research aimed to evaluate the chemical and biological profile of Hylocereus polyrhizus fruits. The samples were acquired in a supermarket of the private network of Manaus-Am. Later they were stabilized and the proposed analyzes were carried out. The results of the chemical analysis point to the presence of phenolic compounds such as flavonoids, tannins, catechins, flavones, flavonols and other phenolic compounds with antioxidant potential and consequently with biological potential for other pathologies related to oxidative stress. The content of phenolic compounds and flavonoids indicate the presence of these substances, which proves the positive result of the phytochemical analysis. Finally, the biological analysis against the DPPH and ABTS radicals indicate that the fruits of Hylocereus polyrhizus have considerable antioxidant action based on the IC50 presenting mainly against the ABTS radical, which corroborates the previous results since hydrophilic compounds such as phenols and flavonoids, tend to have more affinity for this radical. We can conclude that the fruits of Hylocereus polyrhizus have a great pharmaceutical potential, due to the presence of antioxidant substances that can fight free radicals and reduce oxidative stress, which are related to several pathologies such as diabetes, cancer and degenerative diseases. Undoubtedly the fruits of Hylocereus polyrhizus are excellent therapeutic allies within the context of phytotherapy.
