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  • 标题:Molecular and serological diagnostic of leptospirosis: a review (2014–2020)
  • 本地全文:下载
  • 作者:Bárbara Couto Roloff Padilha ; Marcelle Moura Silveira ; Daiane Drawanz Hartwig
  • 期刊名称:Research, Society and Development
  • 电子版ISSN:2525-3409
  • 出版年度:2022
  • 卷号:11
  • 期号:2
  • 页码:1-10
  • DOI:10.33448/rsd-v11i2.25471
  • 语种:English
  • 出版社:Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
  • 摘要:Leptospirosis is a zoonosis caused by pathogenic bacteria of the genus Leptospira. This disease affects several animals and humans. Symptoms of leptospirosis can range from mild to severe, may in some cases lead to death. For the diagnosis of leptospirosis, the microscopic agglutination test is considered the “gold standard”; however, it has limitations and studies are being conducted to develop alternative methods of screening and diagnosis of leptospirosis. Serological and immunochemical tests using Leptospira recombinant antigens in combination to molecular tests may be an alternative. In this study, we reported the advances achieved from 2014 until 2020 in controlling leptospirosis based on serological tests using recombinant antigens and molecular diagnosis.
  • 关键词:Serological tests;Immunochemical tests;Molecular diagnosis;Leptospirosis;Recombinant proteins.
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