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  • 标题:Developing Cardiac Electrophysiology Ontology: Moving Towards Data Harmonization and Integration
  • 本地全文:下载
  • 作者:Hadi Kazemi-Arpanahi ; Mostafa Shanbehzadeh ; Saeed Jelvay
  • 期刊名称:Frontiers in Health Informatics
  • 电子版ISSN:2676-7104
  • 出版年度:2020
  • 卷号:9
  • 期号:1
  • DOI:10.30699/fhi.v9i1.231
  • 语种:English
  • 出版社:Hamara Afzar
  • 摘要:Introduction: Cardiac electrophysiology (EP) studies the electrical heart conduction system which is used for diagnosis and treatment of cardiac arrhythmias. In this context, a huge amount of data is generated, requiring efficient and effective access, interpretation, and data analysis from multiple sources in a unified view. To resolve this challenge, this essay presents an ontology to reconcile data heterogeneity problems in this domain. Material and Methods: The cardiac EP ontology was constructed according to the life cycle of ontology building. Structural, functional, and expert evaluation was performed to ensure its quality and usability.      Results: Cardiac EP ontology was developed using protégé environment and implemented in OWL editing tool. It presented a detailed hierarchical structure of the cardiac EP domain with around 324 instances describing cardiac EP-related concepts. Conclusion: Cardiac EP ontology provides an explicit formal description of the concepts, relationships, and properties associated with cardiac electrophysiology making seamless data integration between multiple heterogeneous databases. It also is a useful framework for knowledge representation in knowledge-based systems, as well as for explicit communication between experts in the EP domain.
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