摘要:Introduction: In Mali, the irrational use of drugs constitutes a public health problem through the misuse of certain psychotropic and / or analgesic drugs for drug addiction purposes. The aim of this study was to measure the consumption of drugs diverted from their therapeutic use in Bamako. Methods: This was a cross-sectional study carried out in Bamako with a sample of 260 respondents: 98 health workers and 162 clients (pharmacies) / patients (hospitals). Results: Men were more affected than women, with 62% of cases. The 15-45 age group accounted for 55% of cases. According to the results, workers and students respectively represented 19% and 17% of cases. Promethazine (20%), the combination Paracetamol / codeine / caffeine (13%) and Tramadol (11%) were the drugs most commonly used and diverted from their medical use among clients of pharmacies. According to pharmacists, the drugs affected by misuse were Misoprostol (10%), Clonazepam (9%) and Promethazine (9%). According to doctors and nurses, Misoprostol, Promethazine and diazepam were used for other purposes with 23%, 16% and 13%, respectively. Conclusion: In order to reduce this practice, a synergy of action by health professionals is essential for the rational use of drugs.