摘要:This research was conducted to find the best combination of coating material and microencapsulation method for synbiotics. This research consists of 3 chapters. Chapter 1, was conducted to obtain the best combination of 3 types of coating materials (whey protein, skim milk, and maltodextrin) with 3 doses of coating material (0%, 10%, and 20%). Chapter 2, was conducted to find the best microencapsulation method that can maintain viability, the density of probiotic bacteria, and physiological and biochemical properties of bacteria. The probiotic bacteria used was Pseudoalteromonas piscisida with the prebiotic mannan-oligosaccharide (MOS). A total of 9 treatments in Chapter 1 was microencapsulated using spray- and drum-drying methods. Chapter 3, was conducted to determine the economic value of the synbiotic microcapsule products. The best result from Chapters 1 and 2 is synbiotics coated with a combination of 20% skim milk and 20% maltodextrin (treatment 6) with the spray drying method compared to other treatments. Treatment 6 is produced the highest percentage of product, the physical characteristics of which were good white powder when stored in cold (4°C) and room (25-29°C) temperatures. The best result in Chapter 3 is treatment 6 that showed profitable, highest R/C ratio and B/C ratio than other treatments. However, even though the quantity of the product is profitable, the resulting product can not live. Our suggestion is to use another method namely, freeze-drying for microencapsulation of heat-resistant bacteria such as the bacteria used in this study.