摘要:Cascade reactions have always had an irreplaceable position in biocatalysis. In this work, we are inspired by the cascade reactions catalyzed by natural enzymes and combining the peroxidase mimetic activity of metal organic frameworks (MOF) nanosheets and the glucose oxidation mimetic enzyme activity of gold nanoparticles (AuNPs) constitutes a dual nanozyme mimetic cascade reaction. AuNPs/Zn-TCPP nanosheets with dual mimetic enzyme activities were prepared by in situ reduction to generate AuNPs on the surface of 2D MOF. And used to further detect the content of hydrogen peroxide or glucose.