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  • 标题:Laboratory-Based Cytological and Biochemical Profile of Cerebrospinal Fluid for Children With Acute Bacterial Meningitis in Bangladesh
  • 本地全文:下载
  • 作者:Mohammad Zakerin Abedin ; Laila Jarin ; Donald James Gomes
  • 期刊名称:Journal of the Asiatic Society of Bangladesh, Science
  • 印刷版ISSN:2408-8676
  • 出版年度:2021
  • 卷号:47
  • 期号:2
  • 页码:137-147
  • DOI:10.3329/jasbs.v47i2.57277
  • 语种:English
  • 出版社:Asiatic Society of Bangladesh
  • 摘要:An attempt was made to analyze the cerebrospinal fluid (CSF) for a cytological and biochemical profile to identify etiological agents from children with suspected acute bacterial meningitis. The cerebrospinal fluid (CSF) samples from 371 suspected meningitis cases were examined, and the highest bacterial meningitis was found in 52(14.0%) cases in this study. Among a total of 371 samples of CSF, 272(73.3%) were crystal clear, 52(14.0%) were moderately turbid, 47(12.7%) highly turbid. The total leukocyte cell count of the CSF was proportionate to the turbidity. In the case of crystal clear CSF’s, total leukocyte counts (TLC) were normally ranging from 100 mg/dL. CSF protein concentration greater than 100 mg/dl and sugar level below 40 mg/dl were considered as suspected bacterial meningitis in this study. Surprisingly, the C-Reactive Protein (CRP) values were found to be >40 mg/dL in both culturally positive and negative cases. Most of meningitis positive cases showed increased total cell counts as well as protein concentration, and decreased serum sugar concentrations.
  • 关键词:Cytological patterns;Biochemical profile;Acute bacterial meningitis
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