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  • 标题:Disrupted computations of social control in individuals with obsessive-compulsive and misophonia symptoms
  • 本地全文:下载
  • 作者:Sarah M. Banker ; Soojung Na ; Jacqueline Beltrán
  • 期刊名称:iScience
  • 印刷版ISSN:2589-0042
  • 出版年度:2022
  • 卷号:25
  • 期号:7
  • 页码:1-16
  • DOI:10.1016/j.isci.2022.104617
  • 语种:English
  • 出版社:Elsevier
  • 摘要:SummaryMisophonia is a disorder in which certain sounds produced by other people lead to intense negative reactions. It remains unknown how misophonia relates to other psychiatric conditions or impairments. To identify latent constructs underlying symptoms, we conducted a factor analysis consisting of items from questionnaires assessing symptoms of misophonia and other psychiatric conditions. One thousand forty-two participants completed the questionnaires and a social exchange task in which they either could (“controllable”) or could not (“uncontrollable”) influence future monetary offers from other people. Misophonia and obsessive-compulsive (OC) symptoms loaded onto the same factor. Compared with individuals with low Miso-OC factor scores, individuals with high scores reported higher perceived controllability of their social interactions during the uncontrollable condition and stronger aversion to social norm violations in the uncontrollable compared with the controllable condition. Together, these results suggest misophonia, and OC symptoms share a latent psychiatric dimension characterized by aberrant computations of social controllability.Graphical abstractDisplay OmittedHighlights•Factor analysis of psychiatric survey items in over 1,000 subjects reveals three factors•Misophonia and obsessive-compulsive (OC) symptoms load onto the same factor•Those with high miso-OC factor scores display illusory perceptions of social control•The same individuals also show increased aversion to unexpected social eventsBiological sciences; Neuroscience; Behavioral neuroscience; Clinical neuroscience; Sensory neuroscience
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