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  • 标题:Palladium-Catalyzed Allylation of Acidic and Less Nucleophilic Anilines Using Allylic Alcohols Directly
  • 本地全文:下载
  • 作者:Yi-Chun Hsu ; Kim-Hong Gan ; Shyh-Chyun Yang
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2005
  • 卷号:53
  • 期号:10
  • 页码:1266-1269
  • DOI:10.1248/cpb.53.1266
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:

    The direct activation of C–O bonds in allylic alcohols by palladium complexes has been accelerated by carrying out the reactions in the presence of titanium(IV) isoproxide and 4 Å molecular sieves. The acidic and less nucleophilic anilines such as diphenylamine, phenothiazine, 4-cyanoaniline, and nitroanilines are efficiently allylated under palladium catalysis using allylic alcohols as allylating reagents.

  • 关键词:palladium-catalyzed; allylation; acidic anilines; C–N bond formation
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