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文章基本信息

  • 标题:Compounds Structurally Related to Tamoxifen as Openers of Large-Conductance Calcium-Activated K+ Channel
  • 本地全文:下载
  • 作者:Yu Sha ; Toshihiko Tashima ; Yumi Mochizuki
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2005
  • 卷号:53
  • 期号:10
  • 页码:1372-1373
  • DOI:10.1248/cpb.53.1372
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:

    We found that a variety of compounds containing partial structures of tamoxifen showed activity as chemical modulators of large-conductance calcium-activated K+ channels (BK channels).

  • 关键词:large-conductance calcium-activated K+ channel; tamoxifen; channel opener; (xeno)estrogen; electrophysiology
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