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  • 标题:Studies on Human Urinary and Renal Esterases That Migrate to the γ-Globulin Region upon Cellulose Acetate Electrophoresis
  • 本地全文:下载
  • 作者:杉浦 衛 ; 飯泉 祐一 ; 足立 哲夫
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1981
  • 卷号:29
  • 期号:10
  • 页码:2920-2927
  • DOI:10.1248/cpb.29.2920
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:

    Large amounts of an esterase that migrated to the γ-globulin region (γ-esterase) upon cellulose acetate electrophoresis were excreted in the urine from patients with renal diseases. The γ-esterase localized in the renal tubules of the kidney in patients with renal tubular diseases was purified and shown to be identical with the urinary esterase that migrated to the γ-globulin region by immunological studies. The esterase has a molecular weight of 66000, an optimum pH of 7.5, and pI values of 7.9 and 8.3.

  • 关键词:immunoelectrophoresis
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