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  • 标题:Biological activities of chitosan-salicylaldehyde schiff base assisted silver nanoparticles
  • 本地全文:下载
  • 作者:Salman S. Alharthi ; Thandapani Gomathi ; J. John Joseph
  • 期刊名称:Journal of King Saud University - Science
  • 印刷版ISSN:1018-3647
  • 出版年度:2022
  • 卷号:34
  • 期号:6
  • 页码:1-8
  • DOI:10.1016/j.jksus.2022.102177
  • 语种:English
  • 出版社:Elsevier
  • 摘要:Graphical abstractDisplay OmittedAbstractObjectivesThe nanobiotechnology era has sparked interest in the green synthesis of stable silver nanoparticles (Ag-NPs) without hazardous chemicals. As a result, the current study used chitosan-salicylaldehyde Schiff base (CSB) as a non-toxic, reducing and stabilizingagent to prepare stable silver nanoparticles.MethodsThe characterization of Ag-NPs impregnated chitosan-salicylaldehyde Schiff base was fulfilled using UV-Vis, FTIR, XRD and TEM studies.ResultsThe absorption band present around 425 nm in UV-Vis spectra indicated the formation of Ag-NPs. The appearance of a new band for the CN bond, deduction in the intensity of the CO group of salicylaldehyde and NH group of chitosan confirmed the formation of Schiff base and Ag-NPs in FTIR analysis. XRD pattern revealed the orientation and crystalline nature of Ag-NPs with 2θ at 38°, 46° and 54° related to Ag-NPs (JCPDS No. 04-0783), whereas the peak at 2θ = 27° associated with CSB. The total porosity of 53.24% was determined using the liquid displacement method. The CSB-Ag-NPs have good scavenging activity (46.25% and 49.35% activity in DPPH assay and H2O2assay), great antibacterial (zone of inhibition 17 mm and 19 mm forE-ColiandPseudomonassp.), antifungal (18 mm forP. notatum), and anti-larvicidal activity, according to biological assessments.ConclusionsThe synthesised Ag-NPs were non-toxic to marine ecosystems in a safety bioassay test.
  • 关键词:KeywordsSilver nanoparticlesChitosanSchiff baseSalicylaldehydeBiological assayBiosafety assay
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