摘要：AbstractWith the advent of the Systems Biology Markup Language (SBML), a large community of SBML-compliant tools has been created. However, these tools can only be used to their full potential by expert users with advanced programming knowledge.OneModelis an open-source text-based tool for defining SBML models in a modular and incremental way that minimizes the user's programming knowledge requirements. It is focused on accessibility, simplicity, and modularity.OneModelsyntax allows the user to define models based on chemical (and pseudo-chemical) reactions, differential equations, and algebraic equations.OneModelis written inPython,and it provides two interfaces: a command-line interface for expert-users, and a graphical user interface for non-expert users. Here, we show twoOneModelsyntax use case scenarios for modeling an antithetic controller and then integrating it into a host-aware model, which is freely distributed withOneModel.
