标题：Subgingival Application of Amla Extract Mediated Copper and Graphene Oxide Nanocomposite Gel in the Treatment of Periodontal Pocket: A Randomized Clinical Study
期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：1
页码：2909-2913
DOI：10.9756/INT-JECSE/V14I1.350
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Background: Beneficial effects of the novel nanocomposite made with copper and graphene oxide nanoparticles using amla extract have already been proven in our previous studies. As only scaling and root planing fails to give expected outcomes in some cases several adjective measures are taken to achieve the optimal outcome. Contact killing properties of copper metal, antioxidant effects of amla are well known. Hence this study evaluated the adjunctive application of the novel gel as an adjunct to the conventional scaling and root planing. To evaluate clinical efficacy of amla extract mediated copper (Cu) and graphene oxide (GO) nanocomposite gel as an adjunct to conventional scaling and root planing to treat periodontal pockets. Materials and Methods: Novel nanocomposite gel was made with 20µL concentration. Selected patients were divided into 2 groups. Each group had 10 individuals with periodontal pockets of ≥5 mm. Group 1 patients were treated with conventional scaling and root planing (SRP). Group 2 individuals were treated with scaling root planing + subgingival application of the novel gel with help of wide bore blunt ended syringe. Subgingival application was done at initial SRP appointment followed by 7 and 14 days. Clinical parameters including probing depth (PD), plaque index (PI) and gingival index (GI) at baseline and 90 days. Results: Significant reduction in GI, PI, and PD was observed when compared to baseline. Intergroup comparison yielded significant reduction in the clinical parameters. Higher reduction in the test group was observed. Conclusion: Subgingival application of Cu and GO nanocomposite containing novel gel as an adjunct to SRP is an effective treatment for treating periodontal pockets.
