期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：3
页码：3266-3277
DOI：10.9756/INT-JECSE/V14I3.407
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Background: This paper reports the synthesis of zinc oxide nanoparticles at room temperature using Stevia and Ficus benghalensis extract. This is cost effective, simple and stable for a long time. In this article synthesis of zinc oxide nanoparticles using Stevia and Ficus benghalensis extract has been done and checked for its anticariogenic activity. Materials and methods: Anticariogenic activity of Stevia and Ficus bengalensis were tested against gram positive and fungal strains by observing the zone of inhibition. On treating Zinc sulphate with stevia and ficus extract reduction of zinc sulphate is observed leading to the formation of stable zinc nanoparticles in solution.The Gram‑positive bacteria used in the test were Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans, and fungal strains Candida albicans were used. Results: Stevia and Ficus bengalensis formulation mediated zinc oxide Nanoparticles showed more anticariogenic activity against bacteria(e.g.E. Faecalis, the zone of diameter 32mm) and (e.g. S.Aureus, the zone of diameter 28mm) when compared to other ZnO formulation mediated extract for S.Mutans and E.faecalis. Conclusion: From our study we can conclude that the extract at different concentrations exhibited significant anticariogenic activity against all the bacterial strains tested. Thus, the result of our present study shows that the ficus and stevia mediated ZnO nanoparticles showed significant anticariogenic activity.
关键词：Stevia and Ficus bengalensis;Zinc oxide nanoparticles;plant extract;Anticariogenic;Free radicals
