期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：4
页码：2395-2399
DOI：10.9756/INTJECSE/V14I4.330
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Sepsis is a severe and dysregulated inflammatory response to infection that is characterized by endorgan failure far from the infection's primary site. Acute kidney damage (AKI) caused by sepsis increases morbidity and mortality in patients, has a major influence on many organ functions, is associated to a lengthier stay in the critical care unit, and consequently consumes large healthcare resources. When compared to AKI caused by nonpeptic bacteria, septic AKI has a distinct pathogenesis that necessitates a different treatment strategy. Despite significant progress in various domains of medicine, the pathogenesis, diagnostic techniques, and suitable treatment strategies in sepsis remain controversial.When compared to other critically ill patients, a number of immunomodulatory drugs that showed promise in preclinical studies fail to diminish the excessively high mortality rate of sepsis and cause AKI.Limited histopathologic knowledge, a scarcity of animal models that accurately replicate human sepsis, and a scarcity of particular diagnostic techniques are all major roadblocks to advances in understanding, early identification, and use of effective therapy modalities in sepsis-induced AKI.The most recent breakthroughs in understanding the fundamental processes of sepsis-induced AKI, as well as the characteristics of relevant animal models and prospective therapeutics, are discussed here. Main symptoms and or important clinical findings:A 22 -year-old male patient had been admitted to the hospital in AVBR hospital on date 21 /10/2021 with chief complaint patient presented with a c/o abdominal pain, fever, chills, in the last 4 days, c/o decreased appetite &generalized, weakness in the last2 day, confused state in the past 1 day, nausea, vomiting, headache, fatigue, swelling, on hand &feet. Physical examination and investigation doctor diagnose a case of septicemia with acute kidney injury. Past history: history of septicemia with acute kidney injury 2 month back for which he was hospitalized after CBC test’s renal function tests,and Athar tests in septicemia with acute kidney injury. The main diagnoses, therapeutic intervention, and outcomes: After physical examination and investigations doctor diagnose a case septicemia with acute kidney injury. Drugs Inj. Piptaz 2.25 gm TDS, Inj. Levoflox 500 mg OD, Inj. Pan 40 mg OD, Inj. Emset 4mg TDS, Inj. Norad infusion at BP, Inj. Lasix 40mg BD, Inj vasopressin at BP, InjNeomol 1 gm stat, Inj D25% IV Stat. Give a drug he was took all treatment and outcomes was good. Her sing and symptoms were reduced. Conclusion: he responded well to all medication and doctor therapy and she made a good recovery.
关键词：sepsis-related acute kidney injury;as well as sepsis-induced acute renal injury
