期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：4
页码：1748-1757
DOI：10.9756/INTJECSE/V14I4.223
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Context: In light of the widespread availability of anti-Streptococcus prophylactic drugs, researchers have begun to focus on developing newer, more effective agents that are also less expensive, more efficient, and safer. Aims: The purpose of this research was to assess the antibacterial activity of a multi-herbal mouth rinse to that of certain standard chemical formulations, including those based on essential oils, fluoride, and 0.2% chlorhexidine digluconate. It is a randomized, controlled, triple-blind experiment of several settings. Methodology: A total of 120 adolescents, aged 15 to 17, were randomly assigned to one of four treatment groups: The recommended dosing schedule is as follows: (a) 15 ml of a multiherbal mouth rinse twice daily; (b) 15 ml of a 0.2% chlorhexidine mouth rinse twice daily; (c) 15 ml of an essential oil mouth rinse twice daily; and (d) 15 ml of a 0.2% sodium fluoride mouth rinse twice daily. The number of oral streptococci CFUs/mL was determined from samples of subject saliva and plaque cultured on TYCSB agar. Statistical Analysis Used: The different mouthrinses were compared using repeated-measures analysis of variance (ANOVA), with the multi-herbal mouthrinse being compared using the Bonferroni post hoc test. P 0.05 was chosen as the significant threshold. Results: The multi-herbal mouth rinse considerably reduced S although there was no statistically significant difference between groups in the pre-treatment measurements. mutans colony count compared to the other mouthrinses (with the exception of the fluoride mouthrinse) up to 1 week postrinsing. Conclusion: The number of S. mutans colony forming units (CFU) was reduced by both chlorhexidine and multiherbal mouth rinses.
