Exposure to whole-body vibration is a risk factor for the development of low back pain. In order to develop a fuller understanding of the response of the seated person to vibration, experiments have been conducted in the laboratory investigating the biomechanics of the seated person. Some of these methods are based on the driving force and acceleration at the seat and are reported in the literature as apparent mass, driving point mechanical impedance or absorbed power. This paper introduces the background behind such impedance methods, the theory and application of the methods. It presents example data showing typical responses of the seated human to whole-body vibration in the vertical, fore-and-aft and lateral directions. It also highlights problems that researchers might encounter in performing, analysing and interpreting human impedance data.