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  • 标题:Green synthesized chitosan modified platinum-doped silver nanocomposite: An investigation for biomedical and environmental applications
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  • 作者:Rajaduraipandian Subramanian ; Amutha Eswaran ; Sabeena G. Kathirason
  • 期刊名称:Journal of King Saud University - Science
  • 印刷版ISSN:1018-3647
  • 出版年度:2022
  • 卷号:34
  • 期号:7
  • 页码:1-9
  • DOI:10.1016/j.jksus.2022.102220
  • 语种:English
  • 出版社:Elsevier
  • 摘要:Graphical abstractDisplay OmittedAbstractEco-friendly and inexpensive syntheses of metal-based nanocomposites is now gaining attention for their potential exploitation in biomedical and environmental fields. In this study, green method was applied to synthesize chitosan-modified platinum-doped silver nanocomposites (Ch-Pt-Ag NCs) using leaf extract ofDesmostachya bipinnata, a plant with several medicinal values. Synthesis of Ch-Pt-Ag NCs was proven by XRD, SEM, FTIR, and TGA characterizations. Photocatalytic and biological activities of green-prepared Ch-Pt-Ag NCs were further explored. Crystallites of Ch-Pt-Ag NCs exhibited a mean size of 24 nm measured by XRD. SEM analysis indicated the formation of cubic and rod-shaped structures of Ch-Pt-Ag NCs. Functional groups present in plant extract were responsible for stabilizing and capping of Ch-Pt-Ag NCs, which were confirmed by FTIR analysis. Green synthesized Ch-Pt-Ag NCs exhibited dose-dependent anti-inflammatory and larvicidal (anti-dengue) activities. Green prepared Ch-Pt-Ag NCs exerted very low toxicity in Brine shrimp lethality assay indicated the biocompatible nature of synthesized nanostructures. The Ch-Pt-Ag NCs were also examined as a photocatalytic agent, resulting in 98% degradation of Rhodamine dye. Green synthesized Ch-Pt-Ag NCs with great biological and photocatalytic activities warrants further research on its biomedical and environmental fields.
  • 关键词:KeywordsNanocompositeBiosynthesisDesmostachya bipinnataPhotocatalysisAnti-inflammatory activityLarvicidal activityBiocompatibility
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