首页    期刊浏览 2025年12月03日 星期三
登录注册

文章基本信息

  • 标题:Nine out of ten samples were mistakenly switched by The Orang-utan Genome Consortium
  • 本地全文:下载
  • 作者:Graham L.Banes ; Emily D.Fountain ; Alyssa Karklus
  • 期刊名称:Scientific Data
  • 电子版ISSN:2052-4463
  • 出版年度:2022
  • 卷号:9
  • 期号:1
  • 页码:1-5
  • DOI:10.1038/s41597-022-01602-0
  • 语种:English
  • 出版社:Nature Publishing Group
  • 摘要:The Sumatran orang-utan (Pongo abelii) reference genome was frst published in 2011, in conjunction with ten re-sequenced genomes from unrelated wild-caught individuals . Together, these published data have been utilized in almost all great ape genomic studies, plus in much broader comparative genomic research . Here, we report that the original sequencing Consortium inadvertently switched nine of the ten samples and/or resulting re-sequenced genomes, erroneously attributing eight of these to the wrong source individuals . Among them is a genome from the recently identifed Tapanuli (P. tapanuliensis) species: thus, this genome was sequenced and published a full six years prior to the species’ description . Sex was wrongly assigned to fve known individuals; the numbers in one sample identifer were swapped; and the identifer for another sample most closely resembles that of a sample from another individual entirely. these errors have been reproduced in countless subsequent manuscripts, with noted implications for studies reliant on data from known individuals .
国家哲学社会科学文献中心版权所有