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  • 标题:A multi-scale probabilistic atlas of the human connectome
  • 本地全文:下载
  • 作者:Yasser alemán-Gómez ; Alessandra Grifa ; Jean-Christophe Houde
  • 期刊名称:Scientific Data
  • 电子版ISSN:2052-4463
  • 出版年度:2022
  • 卷号:9
  • 期号:1
  • 页码:1-16
  • DOI:10.1038/s41597-022-01624-8
  • 语种:English
  • 出版社:Nature Publishing Group
  • 摘要:The human brain is a complex system that can be efciently represented as a network of structural connectivity. Many imaging studies would beneft from such network information, which is not always available . In this work, we present a whole-brain multi-scale structural connectome atlas . This tool has been derived from a cohort of 66 healthy subjects imaged with optimal technology in the setting of the Human Connectome Project . From these data we created, using extensively validated difusion-data processing, tractography and gray-matter parcellation tools, a multi-scale probabilistic atlas of the human connectome . In addition, we provide user-friendly and accessible code to match this atlas to individual brain imaging data to extract connection-specifc quantitative information . This can be used to associate individual imaging fndings, such as focal white-matter lesions or regional alterations, to specifc connections and brain circuits . Accordingly, network-level consequences of regional changes can be analyzed even in absence of difusion and tractography data . This method is expected to broaden the accessibility and lower the yield for connectome research .
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