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  • 标题:Inter-species cell detection - datasets on pulmonary hemosiderophages in equine, human and feline specimens
  • 本地全文:下载
  • 作者:Christian Marzahl ; Jenny Hill ; Jason Stayt
  • 期刊名称:Scientific Data
  • 电子版ISSN:2052-4463
  • 出版年度:2022
  • 卷号:9
  • 期号:1
  • 页码:1-10
  • DOI:10.1038/s41597-022-01389-0
  • 语种:English
  • 出版社:Nature Publishing Group
  • 摘要:Pulmonary hemorrhage (P-Hem) occurs among multiple species and can have various causes. Cytology of bronchoalveolar lavage fuid (BALF) using a 5-tier scoring system of alveolar macrophages based on their hemosiderin content is considered the most sensitive diagnostic method. We introduce a novel, fully annotated multi-species P-Hem dataset, which consists of 74 cytology whole slide images (WSIs) with equine, feline and human samples. to create this high-quality and high-quantity dataset, we developed an annotation pipeline combining human expertise with deep learning and data visualisation techniques. We applied a deep learning-based object detection approach trained on 17 expertly annotated equine WSIs, to the remaining 39 equine, 12 human and 7 feline WSIs . The resulting annotations were semi-automatically screened for errors on multiple types of specialised annotation maps and fnally reviewed by a trained pathologist . Our dataset contains a total of 297,383 hemosiderophages classifed into fve grades . It is one of the largest publicly available WSIs datasets with respect to the number of annotations, the scanned area and the number of species covered.
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