摘要:Genomic tools applied to non-model organisms are critical to design successful conservation strategies of particularly threatened groups . Freshwater mussels of the Unionida order are among the most vulnerable taxa and yet almost no genetic resources are available . Here, we present the gill transcriptomes of fve European freshwater mussels with high conservation concern: Margaritifera margaritifera, Unio crassus, Unio pictorum, Unio mancus and Unio delphinus . The fnal assemblies, with N50 values ranging from 1069–1895 bp and total BUSCO scores above 90% (Eukaryote and Metazoan databases), were structurally and functionally annotated, and made available . The transcriptomes here produced represent a valuable resource for future studies on these species’ biology and ultimately guide their conservation .