摘要:In this study, for the first time, a magnetic ionic liquid-based aqueous biphasic system (MIL-ABS) was developed to extract total flavonoids from crude extracts of yam (Dioscorea alata L.) peel. The effect of various conditions on the separation behavior was systematically examined and optimized. A relatively high extraction efficiency (96.4%) and partition coefficient (K = 33.2) for total flavonoids could be achieved. MI-ABS not only has the advantage of being able to extract quickly in the absence of an organic solvent, but it also responds to a simple external magnetic field. This work has the potential to be a useful reference for practical enrichment or separation of active ingredients.