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  • 标题:Changes in Middle Latency Auditory-Evoked Potentials of the Rat Exposed to Styrene
  • 作者:Yu-ping Wang ; Takeshi Saito ; Toshiyuki Hosokawa
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2001
  • 卷号:47
  • 期号:2
  • 页码:175-183
  • DOI:10.1248/jhs.47.175
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Effects of styrene exposure on middle latency auditory-evoked potentials (MAEPs), which reflect the central auditory function, were investigated. As significant delay in latencies of No, Po, Na, and Pa components and increases in the peak to peak intervals of MAEPs, but not amplitudes, were observed in a dose-dependent manner, The present and our previous studies demonstrate that electrophysiological alterations occur before neuronal cell damage induced by styrene exposure. The present results suggested that styrene has a marked effect on the processing of auditory information related to MAEPs.
  • 关键词:styrene;middle latency auditory-evoked potential;auditory function;toxicity
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