文章基本信息

标题：Induction of Oxidative Stress and Dysfunction of Nitric Oxide-Dependent Vascular Tone Caused by Quinones Contained in Diesel Exhaust Particles
作者：Yoshito Kumagai ; Nobuhiro Shimojo
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：2001
卷号：47
期号：5
页码：439-445
DOI：10.1248/jhs.47.439
出版社：The Pharmaceutical Society of Japan
摘要：This article reviews studies of overproduction of reactive oxygen species during reductive activation of quinones contained in diesel exhaust particles. The resulting inhibition of nitric oxide synthase activity causing suppression of vasorelaxation by phenanthraquinone, one of the quinone in diesel exhaust particles, is also reviewed.
关键词：diesel exhaust particles;quinone;nitric oxide;reactive oxygen species;endothelial dysfunction