文章基本信息

标题：Genetic Evidence of Resistance to Cadmium Toxicity in Wistar-Imamichi Rats
作者：Hideaki Shimada ; Yasutaka Takamure ; Yorishige Imamura 等
期刊名称：Journal of Health Science
印刷版ISSN：1344-9702
电子版ISSN：1347-5207
出版年度：2003
卷号：49
期号：4
页码：316-318
DOI：10.1248/jhs.49.316
出版社：The Pharmaceutical Society of Japan
摘要：Resistance to the toxicity of cadmium (Cd) was examined in male Wistar-Imamichi (Wistar-IM) and Fischer 344 (Fischer) rats. The Wistar-IM strain was confirmed to exhibit strong resistance compared to the Fischer strain. The resistance in first filial (F1) males was intermediate between that in Wistar-IM and that in Fischer males. The data from reciprocal crosses indicate that the strong resistance to Cd toxicity in male Wistar-IM rats is autosomal and inherited as an incompletely dominant phenotype.
关键词：cadmium;Wistar-Imamichi rat;resistance;first filial progeny;incompletely dominant phenotype