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  • 标题:Identification of Oil-Soluble Coal Tar Dyes in Cosmetics Using Reversed-Phase TLC/Scanning Densitometry
  • 作者:Tsutomu Ohno ; Eiichi Mikami ; Hiroshi Matsumoto
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2003
  • 卷号:49
  • 期号:5
  • 页码:401-404
  • DOI:10.1248/jhs.49.401
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:A simple and rapid analytical method of oil-soluble coal tar dyes in cosmetics was established using reversed-phase TLC/scanning densitometry. Eleven kinds of oil-soluble coal tar dyes were able to be separated completely on reversed-phase TLC plates by the complementary use of 2 solvent systems. The solvent systems were A; n -hexane/2-butanone solution (5 : 1, v/v), solvent system B; acetonitrile/methanol solution (5 : 1, v/v). Then we measured visible absorption spectra of spots developed on the reversed-phase TLC plates by scanning densitometer to identify these coal tar dyes. The proposed method was successfully applied to the identification of oil-soluble coal tar dyes in commercial cosmetics.
  • 关键词:oil-soluble coal tar dye;reversed-phase TLC;scanning densitometry;cosmetic
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