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  • 标题:Photodecomposition and Bioconcentration of a Bisphenol A Metabolite in Medaka, Oryzias latipes
  • 作者:Yuji Takao ; Miki Shimazu ; Shinya Kohra
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2004
  • 卷号:50
  • 期号:6
  • 页码:576-580
  • DOI:10.1248/jhs.50.576
  • 语种:English
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:

    Exposure experiments in medaka and photodecomposition tests were performed using a metabolite of bisphenol A [4-methyl-2,4-bis( p -hydroxyphenyl)-pent-1-ene; MBP], the solubility limit of which is 42 mg/l of water. Three adult medaka were kept in a 2 l glass beaker at 25 ± 1°C for 4 days. The LC50 for 96 hr was > 1000 ppb. The measured average MBP concentration in the breeding water (nominal concentration of 100 ppb) was 49.2 ppb. The average concentration in the whole bodies of medaka after 4 days was 1.92 mg/g-wet body, and the bioconcentration factor (BCF) of MBP was calculated to be 39.0. MBP in water and acetone was decomposed very easily, with about 98% of the MBP being decomposed after several hours under sunlight. MBP was also decomposed after 48 hr of illumination under a white fluorescent lamp.

  • 关键词:bisphenol A metabolite;bioconcentration factor;photodecomposition
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