摘要：Stress is one of the basic factors in the etiology of number of diseases. The present study was aimed to investigate the antioxidant properties of Triphala ( Terminalia chebula , Terminalia bellerica and Emblica officinalis ) during cold-stress. Four groups of albino rats were employed namely control, Triphala, cold-stress and Triphala with cold-stress. The oxidative stress was assessed by measuring the lipid peroxidation (LPO), enzymatic superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and non-enzymatic (Vitamin C) antioxidant status in adrenal tissue and plasma corticosterone level. Following cold-exposure (8°C for 16 hr/d/15 days), enzymatic and non-enzymatic antioxidants were significantly reduced with concomitant increase in LPO and corticosterone levels were observed. Administration of Triphala (1 g/kg/body weight/48 days) significantly prevents the cold-stress-induced oxidative stress and elevation in LPO and corticosterone levels. This study concludes that Triphala supplementation significantly prevents the cold-stress-induced oxidative stress may due to its antioxidant properties.
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