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  • 标题:Anxiolytic and Antiseizure Effects of Sida tiagii Bhandri
  • 作者:Ashok Kumar Datusalia ; Pankaj Kalra ; Balasubramanian Narasimhan
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2008
  • 卷号:54
  • 期号:5
  • 页码:544-550
  • DOI:10.1248/jhs.54.544
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The central nervous system (CNS) pharmacological effects of ethylacetate extract (EAS) of Sida tiagii Bhandri collected from northern province (Rajasthan) of India were assessed by elevated plus-maze, pentobarbitone induced sleeping time, spontaneous motor activity, pentylenetetrazole-induced seizure, forced swim test and rotarod tests. The results of the present study demonstrated the CNS depressant potential, i.e. , anxiolytic, antiseizure, reduction in spontaneous locomotion and potentiation of pentobarbital-induced hypnosis of the plant under investigation.
  • 关键词:Sida tigaii Bhandari;ethylacetate extract;central nervous system depressant
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