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  • 标题:Cholinesterase-inhibiting Potentials of Amberlite XAD-2 Resin Extracts Collected from River and Drinking Waters in Northwest District of Chiba Prefecture, Japan
  • 本地全文:下载
  • 作者:Ayako Kanno ; Iwaki Nishi ; Tomohiro Kishi
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2010
  • 卷号:56
  • 期号:6
  • 页码:664-674
  • DOI:10.1248/jhs.56.664
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Amberlite XAD-2 resin extracts of river and drinking water sampled in each month during the period from January to December 2008 from the Northwest district of Chiba Prefecture were investigated to characterize and determine their cholinesterase (ChE)-inhibiting potentials and pesticide levels. The XAD-2 extracts from river water collected during the mid-spring to mid-summer periods exhibited strong inhibition effect to horse serum ChE, reflecting the application of organophosphorus and carbamate pesticides to paddy fields. Gas chromatographicmass spectrometric (GC/MS) determinations of the XAD-2 extracts of the river water collected during spring to summer periods also showed to be comparatively high levels of agricultural chemicals, such as herbicides, insecticides and fungicides, as compared with those detected in the drinking water. Although a considerable reduction in the ChE-inhibiting potentials and in the GC/MS detectable compound levels was observed for the river water samples, it is particularly interest that ChE-inhibiting potentials still remained in the drinking water.
  • 关键词:river water;drinking water;XAD-2 resin extract;ChE-inhibiting activity;pesticide concentration
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