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  • 标题:Challenges in the Detection of SARS-CoV-2: Evolution of the Lateral Flow Immunoassay as a Valuable Tool for Viral Diagnosis
  • 本地全文:下载
  • 作者:Nayeli Shantal Castrejón-Jiménez ; Blanca Estela García-Pérez ; Nydia Edith Reyes-Rodríguez
  • 期刊名称:Biosensors
  • 电子版ISSN:2079-6374
  • 出版年度:2022
  • 卷号:12
  • 期号:9
  • DOI:10.3390/bios12090728
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:SARS-CoV-2 is an emerging infectious disease of zoonotic origin that caused the coronavirus disease in late 2019 and triggered a pandemic that has severely affected human health and caused millions of deaths. Early and massive diagnosis of SARS-CoV-2 infected patients is the key to preventing the spread of the virus and controlling the outbreak. Lateral flow immunoassays (LFIA) are the simplest biosensors. These devices are clinical diagnostic tools that can detect various analytes, including viruses and antibodies, with high sensitivity and specificity. This review summarizes the advantages, limitations, and evolution of LFIA during the SARS-CoV-2 pandemic and the challenges of improving these diagnostic devices.
  • 关键词:lateral flow immunoassay;biosensors;COVID-19;SARS-CoV-2;diagnosis;antibodies
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