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  • 标题:Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke
  • 本地全文:下载
  • 作者:Chen Y ; Yang L ; Liang YY
  • 期刊名称:Scandinavian journal of Work, Environment and Health
  • 印刷版ISSN:0355-3140
  • 出版年度:2022
  • 卷号:48
  • 期号:5
  • 页码:372-379
  • DOI:10.5271/sjweh.4025
  • 语种:English
  • 出版社:National Board of Occupational Safety and Health
  • 摘要:This study showed that night shift work interacted with MTNR1B rs10830963 in predisposing to stroke. Particularly, the individuals with the CC genotype suffered a more pronounced risk of incident stroke when exposed to night shift work. Our findings extended the current knowledge about circadian biology in stroke and suggested a need to consider personalized circadian factors in stroke prevention.
  • 关键词:circadian rhythm;incident stroke;melatonin;melatonin receptor 1B gene;MTNR1B rs10830963;nigh shift;polymorphism;stroke;UK Biobank
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