标题：Influência do Parâmetro de Equilíbrio Hidrofílico- Hidrofóbico (HLB) dos Polímeros F98 e F127 na eficácia da formação de nanopartículas de ouro e encapsulamento do fármaco capecitabina para tratamento de câncer de estomâgo
出版社：Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências
摘要：Pluronic F98 and F127 have a higher hydrophilic percentage (70 wt%), in the case of Pluronic F127 and 80% in the case of F98. The article consists of a comparison of the LBL parameter and its influence on the formation of Gold Nanoparticles. These nanoparticles are chosen because they have low toxicity, as well as being effective in medicinal application. Stomach cancer has a high incidence. There is the formation of compounds with a hydrophobic core of polypropylene oxide (PPO) and a hydrophilic crown of polyethylene oxide (PEO). The Pluronic-Nanoparticle system will be gradually released in the patient's body, for less toxicity and greater treatment efficacy. The methodologies used in this first phase are the bibliographic sources and their survey and the use of the main databases for this purpose.
