文章基本信息
- 标题：Antibacterial Activity of Compounds possessing a Tricarbonylmethane Group. XI. Synthesis of a Compound having Structure analogous to A-Ring of Tetracycline.
- 本地全文：下载
- 作者：Tyunosin Ukita ; Kiichi Arakawa
- 期刊名称：Chemical and Pharmaceutical Bulletin
- 印刷版ISSN：0009-2363
- 电子版ISSN：1347-5223
- 出版年度：1957
- 卷号：5
- 期号：6
- 页码：535-538
- DOI：10.1248/cpb1953.5.535
- 语种：English
- 出版社：The Pharmaceutical Society of Japan
- 摘要：
Two synthetic routes to a compound having the structure analogous to the A-ring of tetracycline, 2-phenylcarbamoyl-5, 5-dimethyl-6-(1-piperidyl)-1, 3-cyclohexanedione, were established. The desired compound was obtained by amination of 2-phenylcarbamoyl-5, 5-dimethyl-6-bromo-1, 3-cyclohexanedione with piperidine. The antibacterial properties of the final product are reported.
