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  • 标题:A Water-Soluble Extract from Grifola frondosa, Maitake Mushroom, Decreases Lipid Droplets in Brown Adipocyte Tissue Cells
  • 本地全文:下载
  • 作者:Katsuhiko MINAMINO ; Yumi NAGASAWA ; Masaru OHTSURU
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2008
  • 卷号:54
  • 期号:6
  • 页码:497-500
  • DOI:10.3177/jnsv.54.497
  • 出版社:Center for Academic Publications Japan
  • 摘要:We investigated the effect of a water-soluble extract from Grifola frondosa , the maitake mushroom, on lipid droplets in brown adipocyte tissue (BAT) cells. This water-soluble extract inhibits the conversion of pre white adipocyte tissue (WAT) cells but does not inhibit that of pre BAT cells. It reduces the amount of accumulated triglycerides (TG) in BAT cells. The glycerol-3-phosphate dehydrogenase (GPDH) activities of BAT cells decreased, but the expression of uncoupling protein 1 (UCP1) levels increased. These results suggest that maitake extract inhibits TG accumulation-related energy metabolism.
  • 关键词:maitake (Grifola frondosa);water-soluble extract;adipocyte conversion;triglyceride (TG);uncoupling protein 1 (UCP1)
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