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  • 标题:Occupational Exposure and Thoracic Malignancies, Is There a Relationship?
  • 本地全文:下载
  • 作者:Sevin Baser ; Ozlem Duzce ; Fatma Evyapan
  • 期刊名称:Journal of Occupational Health
  • 印刷版ISSN:1341-9145
  • 电子版ISSN:1348-9585
  • 出版年度:2013
  • 卷号:55
  • 期号:4
  • 页码:301-306
  • DOI:10.1539/joh.13-0097-FS
  • 出版社:Japan Society for Occupational Health
  • 摘要:

    Objectives: The aim of this study was to evaluate the effect of occupational exposure in the occurrence of lung cancer. Method: Three-hundred lung cancer cases diagnosed between September 1, 1999, and September 31, 2007, and 300 healthy controls were enrolled in this case-control study. Life-long occupational history, gender, age, exposure to asbestos, comorbidities, and smoking status were collected. Results: The mean age of the 300 lung cancer cases was 60.3 ± 9.9 year (91.7% male and 8.3% female), and the mean age of healthy control group was 60.4 ± 10.5 year (95.0% male and 5.0% female). The most frequent histological types were squamous (172, 57.3%), adeno (69, 23.1%), and small cell (37, 12.3%). There was an increased risk of lung cancer occurrence among agriculture workers (OR=1.89, 95% Cl=1.17-2.98) ( p =0.009). Inorganic dust exposure (OR=1.81, 95% Cl=1.0-3.25) ( p =0.049) and organic dust exposure (OR=1.89, 95% Cl=1.0-3.59) ( p =0.05) were found to be related with high frequency of having lung cancer. Conclusion: Workers who had occupational exposure to organic and inorganic dust, especially in the agricultural field, had higher risk of lung cancer occurrence when compared with office workers.(J Occup Health 2013; 55: 301-306)

  • 关键词:Inorganic dust; Lung cancer; Occupational exposure; Organic dust
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