The purpose of this research was to examine the relation between anxieties andpsychological mid-life crises, which middle-aged Japanese male workers might experienceand have to cope with.The hypothesis was that (1) there is a correlation between mid-lifecrisis and mental illness in Japanese male workers, (2) the mid-life crises they have to facewould be caused by their environmental or economical issues. The questionnaire survey was administered to 207 employees, aged 33-59 years, by mail.Path analyses were used to examine the relationships.The major fmdings are as follows;(1) there is a relationship between mid-life crisis and mental illness, (2) in the age group 40-49, mental crisis is caused by labor and fmancial anxiety, passing through physical and mentalcapacities, (3) in the age group 50-59, mental crisis is caused by fmancial and familialanxiety passing through physical and mental capacities.