摘要：Unique physiological functions of DHA-bound phospholipids, comparable with those of fish oil (triglyceride), have been reported in several papers. We investigated the effect of DHA-bound phospholipids (squid-PL) on PAF receptor in the present study. We found that squid-PL reduced the incidence of PAF binding to PAF receptor by 63% (200μg/ml). We further found that the PL concentration of 1000g/ml, reduced PAF-induced platelet aggregation by 55%. These physiological effects of squid-PL were able to reduce the fatality rate in mouse following PAF administration. An antagonistic effect of squid-PL against PAF receptor was thus demonstrated.
