The purposes of this study are to investigate the movement characteristics of buttoning and unbuttoning using one hand, as well as to examine the relationship between the required time for the movement and the overlap, habits when putting on and taking off clothes, and handedness. In addition, movement characteristics were compared with the movement of the hand when performing daily activities using a questionnaire. In the experiment, front-opening clothes of two types having different overlaps were used. Subjects were thirty-one healthy male university students( twenty were right-handed, eleven were left-handed). Each subject was asked to button and unbutton each shirt with both hands and one hand. They were then required to answer a sensory evaluation sheet regarding the difficulty of performing the operations with one hand. The subjects also answered a questionnaire concerning 14 daily activities done with the hands, including 5 activities involving the putting on and taking off of clothes. The results were as follows: 1)Regarding the time required to perform operations with one hand, the only significant difference was found when buttoning with a right overlap (left>right). Buttoning with a left overlap and unbuttoning showed no significant difference; 2)The subjects felt that it was difficult to use their right hand when there was a right overlap; 3)Regarding daily activities with one hand, performing the operations of tool was used by left or right hand.The other, the subjects had no preference when it came to putting on and taking off clothes. This was particularly true for the buttoning and unbuttoning of shirts.