A simple and rapid flow injection analysis (FIA) with fluorescence detection was developed for the determination of nitrite in meat and fish products ( e.g. , ham and sausages). 1, 2-Diamino-4, 5-dimethoxybenzene (DDB) was used as the fluorogenic reagent, and the carrier solution was 0.05 mm DDB in 0.5 M sulfuric acid which retained its availability for at least 48 h after preparation. The DDB derivative was monitored at 402 nm (ex. at 311 nm). The calibration curve for standard nitrite ranging from 023 to 4.60 μg/ml showed good linearity ( r = 0.998) between the concentration of nitrite and the fluorescence intensity. The limit for the detection of nitrite was 51 ng/ml at a signal-to-noise ratio of 3. The amount of nitrite in meat and fish products ranged from 7.8 to 24.1 μg/g. Good correlation ( r = 0.991) was obtained between the proposed method and spectrophotometry by using a fish product spiked with a known concentration of standard nitrite.