文章基本信息
- 标题：クズから抽出したイソフラボンがグリオキサラーゼI活性と培養細胞の増殖に及ぼす影響
- 本地全文：下载
- 作者：飯尾 雅嘉 ; 金城 順英 ; 野原 稔弘 等
- 期刊名称：日本栄養・食糧学会誌
- 印刷版ISSN：0287-3516
- 电子版ISSN：1883-2849
- 出版年度：1991
- 卷号：44
- 期号：2
- 页码：123-125
- DOI：10.4327/jsnfs.44.123
- 出版社：Japanese Society of Nutrition and Food Science
- 摘要：
Eight isoflavones extracted from kudzu, Pueraria lobata (WILLD.) OHWI, were tested for their effect on glyoxalase I [E.C. 4. 4. 1. 5] (G-I) activity. One of the isoflavones, 8-C-glucosyl-7, 3′, 4′-trihydroxyisoflavone, (PG-1) strongly inhibited the action of the enzyme at 100μM. However, its inhibitory activity was reduced at lower concentrations in comparison with that of baicalein or quercetin. Some of the remaining isoflavones had a moderate inhibitory effect on G-I, whereas others had a weak effect. All eight isoflavones were also tested for their effect on the growth of HF, a hybridoma cell line. However, none of them inhibited the growth of the hybridoma.
