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  • 标题:ラットのエタノール代謝に及ぼすスピルリナ ( Spirulina platensis ) の影響
  • 本地全文:下载
  • 作者:荒木 仁子 ; 伊東 栄子 ; 高桑 雄一
  • 期刊名称:日本栄養・食糧学会誌
  • 印刷版ISSN:0287-3516
  • 电子版ISSN:1883-2849
  • 出版年度:1994
  • 卷号:47
  • 期号:5
  • 页码:395-400
  • DOI:10.4327/jsnfs.47.395
  • 出版社:Japanese Society of Nutrition and Food Science
  • 摘要:

    The effects of Spirulina platensis on ethanol metabolism were studied in rats. Male Wistar rats aged 5 weeks were fed on a basal diet or a Spirulina -containing diet for 28 days. The blood ethanol level at 30min after intraperitoneal injection of ethanol (200mg/100g body weight) was decreased by Spirulina feeding. To determine whether Spirulina affects ethanol metabolism, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities were measured in rats fed ethanol plus Spirulina for 21 days. Spirulina feeding decreased the Km value of ALDH to acetaldehyde from 0.91mM to 0.70mM. On the other hand, Spirulina feeding did not alter ADH activity. These results suggest that Spirulina may accelerate ethanol metabolism, resulting in rapid clearance of ethanol from blood into the liver.

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