The Image Permanence Institute at Rochester Institute of Technology is a non-profit academic research institute devoted to the study of the preservation of imaging media. The major projects now in progress at IPI are reviewed, falling in three main areas: post-process image stabilizing treatments for silver microfilm, environmental factors in support deterioration of cellulose acetate safety films, and test methods to evaluate photographic storage enclosures such as envelopes, boxes, and albums. IPI has developed a new technology for stabilizing microfilm images against oxidative attack in the form of redox blemishes or overall fading. Known as polysulfide treatment, the essential feature is the conversion of more than half of the image silver to silver sulfide, without affecting image color or density. IPI has also done extensive research to quantify the temperature and humidity dependence of acetate support degradation; a surprisingly strong humidity dependence was observed, along with expected temperature dependence. A brief overview of research in other laboratories is given.