The collagens solubilized from pork skin and fish scale by protease are jetted by High Pressure Slurry Jet Pump. The jet treatment was performed under the condition of acid and neutral pH using these collagens at the temperature lower than denaturation of collagen. The cleavage behavior of collagen molecule was analyzed by SDS-PAGE, change of specific optical rotation and GPC. The collagen from pork or the neutral pH treatment showed the higher stability to jet.