This study examined the effects that irrational beliefs had on responses to stressors in junior high school students. Irrational beliefs and responses to stressors were measured in a survey of 520 junior high school students. About three month later, responses to stressors were measured again, along with the occurrence of stressors during the interval. A hierarchical regression analysis indicated an interaction effect of irrational beliefs and stressor scores on post-interval depression-anxiety, and high irrational beliefs led to the expression of more depression-anxiety.