Many studies on organizational stress have been accumulated in last two decades. This field of study, however, is now facing serious problems with respect to its model development and methodology of stress measurement. The purpose of this study was to explore the feasibility of application of IRT analysis to an organizational stress research for overcoming the problems. The data on PSRS (Psychological Stress Response Scale) obtained from 1, 410 employees working for a computer manufacturing company were analyzed by IRT. The results suggested;(1) Seven out of 53 PSRS items does not maintain appropriateitem characteristics, and (2) PSRS is useful for measuring the persons whose latent trait (stress response) are relatively high. It was also discussed that procedures of IRT analysis could be utilized not only to item analysis but also to model development of study on organizational stress.